A 70-year-old Weslaco doctor who is accused of running a cash-only clinic in Houston that illegally sold millions of opioid pills pleaded not guilty on Monday, federal court records show.

James Robles was indicted on March 25 on federal charges of conspiracy to distribute controlled substances, distributing controlled substances, and maintaining a drug-involved premises.

As of Monday night, the indictment against robles remains sealed.

According to a news release from the U.S. Department of Justice, federal prosecutors say Robles operated the clinic and sold prescriptions for oxycodone, hydrocodone and carisoprodol to “crew leaders” who recruited people to pose as patients. The crew leaders then filled the prescriptions at pharmacies and resold the drugs on the black market, prosecutors say.

“Robles often did not see or examine his purported patients before prescribing them opioids and other controlled substances,” the news release stated. “In just over four years, Robles allegedly prescribed approximately 2.9 million pills of hydrocodone, 1.3 million pills of oxycodone and 1.1 million pills of carisoprodol.”

More than $2 million in cash was deposited into bank accounts controlled by Robles within a three-year period, the news release added.

If convicted, Robles faces up to 20 years in prison on each count.

Federal court records show Robles was released on a $250,000 bond. His next hearing is on June 8, 2026, with a trial set to begin on June 15.